Publications
List of publications per year
Alvarez-Fernandez, M. and Malumbres, M. (2020) Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition. Cancer Cell 37, 514-529 [PMID: 32289274][Full text]
Arriazu E, Vicente C, Pippa R, Peris I, Martínez-Balsalobre E, García-Ramírez P, Marcotegui N, Igea A, Alignani D, Rifón J, Mateos MC, Cayuela ML, Nebreda AR, Odero MD. (2020) A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia. Blood Cancer J. 10(1):3. [PMID: 31913266]
Athie A, Marchese FP, González J, Lozano T, Raimondi I, Juvvuna PK, Abad A, Marin-Bejar O, Serizay J, Martínez D, Ajona D, Pajares MJ, Sandoval J, Montuenga LM, Kanduri C, Lasarte JJ, Huarte M. (2020) Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion. J Cell Biol. 219(9):e201908078. [PMID: 32858747]
Espinosa-Sánchez A, Suárez-Martínez E, Sánchez-Díaz L, Carnero A. (2020) Therapeutic Targeting of Signaling Pathways Related to Cancer Stemness. Front Oncol. 10:1533. eCollection 2020. [PMID: 32984007]
Ezquerra A, Viais R, Lüders J. (2020) Assaying Microtubule Nucleation. Methods Mol Biol.; 2101:163-178. doi: 10.1007/978-1-0716-0219-5_11. [PMID: 31879904]
Felipe-Abrio B, Carnero A. (2020) The Tumor Suppressor Roles of MYBBP1A, a Major Contributor to Metabolism Plasticity and Stemness. Cancers (Basel). 12(1):254. [PMID: 31968688]
García-Heredia JM, Carnero A. (2020) Role of Mitochondria in Cancer Stem Cell Resistance. Cells 9(7):1693. [PMID: 32679735]
García-Heredia JM, Otero-Albiol D, Pérez M, Pérez-Castejón E, Muñoz-Galván S, Carnero A. (2020) Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells. Oncogenesis. 9(10):96. [PMID: 33106480]
Garrido A, Djouder N. (2020) Cirrhosis: A Questioned Risk Factor for Hepatocellular Carcinoma. Trends Cancer. S2405-8033(20)30237-5 [PMID: 32917550]
Gonzalez L, Nebreda AR. RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2. (2020) Semin Cell Dev Biol. 107:21-27. [PMID: 32317145]
González-Martínez, J., Cwersch, A., Martinez-Alonso, D., Lopez, L.R., Almagro, J., Megías D., Boskovic, J., Gilabert, J., Graña-Castro, O., Pierani, A., Behrens, A., Ortega, S. and Malumbres, M. (2020) Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135. bioRxiv [Full text]
Grossi E, Raimondi I, Goñi E, González J, Marchese FP, Chapaprieta V, Martín-Subero JI, Guo S, Huarte M. (2020) A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions. Nat Commun. 11(1):936. [PMID: 32071317]
Hermida, D., Mortuza, G.B., Pedersen, A.K., Pozdnyakova, I., Nguyen, T.T.T.N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, K., Olsen, J.V., Malumbres, M. and Montoya, G. (2020) Molecular basis of the mechanisms controlling MASTL. Mol. Cell. Proteomics 19, 326-343. [PMID: 31852836][Full text]
Kalisz M, Bernardo E, Beucher A, Maestro MA, Del Pozo N, Millán I, Haeberle L, Schlensog M, Safi SA, Knoefel WT, Grau V, de Vas M, Shpargel KB, Vaquero E, Magnuson T, Ortega S, Esposito I, Real FX, Ferrer J. (2020) HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer. EMBO J. 39(9):e102808. [PMID: 32154941 ]
Lioux G, Liu X, Temiño S, Oxendine M, Ayala E, Ortega S, Kelly RG, Oliver G, Torres M. (2020) A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics. Dev Cell. 52(3):350-363.e6. [PMID: 31928974]
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. 2020 Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases. Nat Cell Biol. 22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. [PMID: 32989249]
Lüders J. (2020) Nucleating microtubules in neurons: Challenges and solutions. Dev Neurobiol. Apr 23. [PMID: 32324945]
Marqués M, Tranchant R, Risa-Ebrí B, Suárez-Solís ML, Fernández LC, Carrillo-de-Santa-Pau E, Del Pozo N, Martínez de Villarreal J, Meiller C, Allory Y, Blum Y, Pirker C, Hegedus B, Barry ST, Carnero A, Berger W, Jean D, Real FX. (2020) Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features. Cancer Res. 80(4):843-856. [PMID: 31911549]
Marruecos L, Bertran J, Guillén Y, González J, Batlle R, López-Arribillaga E, Garrido M, Ruiz-Herguido C, Lisiero D, González-Farré M, Arce-Gallego S, Iglesias M, Nebreda AR, Miyamoto S, Bigas A, Espinosa L. (2020) IκBα deficiency imposes a fetal phenotype to intestinal stem cells. EMBO Rep. 21(6):e49708. [PMID: 32270911]
Martínez-Alonso, D. and Malumbres, M. (2020) Mammalian cell cycle cyclins. Semin Cell Dev Biol 22, S1084-9521, 30208-3 [PMID: 32334991 ][Full text]
McGinley AM, Sutton CE, Edwards SC, Leane CM, DeCourcey J, Teijeiro A, Hamilton JA, Boon L, Djouder N, Mills KHG. (2020) Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells. Immunity. 52(2):342-356.e6. [PMID: 32023490 ]
Muñoz-Galván S, Felipe-Abrio B, Verdugo-Sivianes EM, Perez M, Jiménez-García MP, Suarez-Martinez E, Estevez-Garcia P, Carnero A. (2020) Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness. Mol Cancer. 19(1):7. [PMID: 31926547]
Muñoz-Galván S, Carnero A. (2020) Targeting Cancer Stem Cells to Overcome Therapy Resistance in Ovarian Cancer. Cells 9(6):1402. [PMID: 32512891]
Muñoz-Galván S, Rivero M, Peinado-Serrano J, Martinez-Pérez J, Fernández-Fernández MC, Ortiz MJ, García-Heredia JM, Carnero A. (2020) PAI1 is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment with PIM Inhibitor AZD1208. Cells 9(5):1071. [PMID: 32344898]
Parcerisas A, Pujadas L, Ortega-Gascó A, Perelló-Amorós B, Viais R, Hino K, Figueiro-Silva J, La Torre A, Trullás R, Simó S, Lüders J, Soriano E. (2020) NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3. Cereb Cortex. 30(6):3781-3799. [PMID: 32043120]
Pascual R, Martín J, Salvador F, Reina O, Chanes V, Millanes-Romero A, Suñer C, Fernández-Miranda G, Bartomeu A, Huang YS, Gomis RR, Méndez R. (2020) The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer. Sci Adv. 6(20):eaax3868 [PMID: 32440535]
Perez M, García-Heredia JM, Felipe-Abrio B, Muñoz-Galván S, Martín-Broto J, Carnero A. (2020) Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment. Signal Transduct Target Ther. 5(1):195. [PMID: 32963243]
Pérez-Martínez L, Romero L, Muñoz-Galván S, Verdugo-Sivianes EM, Rubio-Mediavilla S, Oteo JA, Carnero A, Blanco JR. (2020) Implications of maraviroc and/or rapamycin in a mouse model of fragility. Aging (Albany NY). 12(9):8565-8582. [PMID: 32353830]
Quintanal-Villalonga Á, Ferrer I, Guruceaga E, Cirauqui C, Marrugal Á, Ojeda L, García S, Zugazagoitia J, Muñoz-Galván S, Lopez-Rios F, Montuenga L, Vicent S, Molina-Pinelo S, Carnero A, Paz-Ares L. (2020) FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy. EBioMedicine. 53:102683 [PMID: 32114392]
Salazar-Roa, M., Trakala, M., Álvarez-Fernández, M., Valdés-Mora, F., Zhong, C., Muñoz, J., Yu, Y., Peters, T.J., Graña-Castro, O., Serrano, R., Zapatero-Solana, E., Abad, M., Bueno, M.J., Gómez de Cedrón, M., Fernández-Piqueras, J., Serrano, M., Blasco, M.A., Wang, D.Z., Clark, S.J., Izpisua-Belmonte, J.C., Ortega, S., Malumbres, M. (2020) EMBO J. e104324.. [bioRxiv 826446] [PMID: 32614092]
Salvador-Barbero, B., Álvarez-Fernández, M., Zapatero-Solana, E., El Bakkali, A., Menéndez, M.C., López-Casas, P.P., Di Domenico, T., Xie, T., VanArsdale, T., Shields, D.J., Hidalgo, M. and Malumbres, M. (2020) CDK4/6 inhibitors impair recovery from cytotoxic chemotherapy in pancreatic adenocarcinoma. Cancer Cell 37, 340-353. [PMID: 32109375]
Sanz-Gómez, N., de Pedro, I., Ortigosa, B., Santamaría, D., Malumbres, M., de Carcer, G. and Gandarillas, A. (2020) Squamous differentiation requires G2/mitosis slippage to avoid apoptosis. Cell Death Differ., doi: 10.1038/s41418-020-0515-2, in press. [PMID: 32080348]
Urosevic J, Blasco MT, Llorente A, Bellmunt A, Berenguer-Llergo A, Guiu M, Cañellas A, Fernandez E, Burkov I, Clapés Cabrer M, Cartañá M, Figueras-Puig C, Batlle E, Nebreda AR, Gomis RR. (2020) ERK1/2 signaling induces upregulation of ANGPT2 and CXCR4 to mediate liver metastasis in colon cancer. Cancer Res canres.4028.2019. [PMID: 32816905]
Vitos-Faleato J, Real SM, Gutierrez-Prat N, Villanueva A, Llonch E, Drosten M, Barbacid M, Nebreda AR. 2020 Requirement for epithelial p38α in KRAS-driven lung tumor progression. Proc Natl Acad Sci U S A. 117(5):2588-2596. [PMID: 31969449]
Zubiaga AM. (2020) Foreword Special Issue Cell Cycle and Regulation. Genes. 11(3):254. [PMID: 32120963]
Ana Filipa Batalha
María Maroto
Beatríz Salvador
